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    The Guadalupe on Main

    4.6 (280 reviews)
    ModerateBars, Mexican
    Closed Closed
    Updated 2 months ago

    The Guadalupe on Main Photos

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    THE GUADALUPE ON MAIN ATMOSPHERE

    What's the vibe?
    Moderate noise
    Hipster
    Casual
    Classy

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    Chantel Q.

    It was our first time here and they exceeded all of our expectations. Service was a 10/10 the entire time. They check on you, and make sure that you get what you need. It was Friday and we were leaning towards meatless options. My husband had the shrimp fajitas and an old fashioned to drink. He was very happy with his selections. The kids and I had bean and cheese burritos and our youngest had an enchilada. We all enjoyed the chips and salsa. Our daughter and my husband loved the Queso but was a little too thick for me, I really like a creamy queso. Last but not least the vibe and decor of the restaurant is really upbeat and beautiful. I am sure we will be back again, thank you!

    Vice & Virtue & classic margarita
    Lenore B.

    My husband and I practically treat this place as our Friday night hangout. We still love grabbing seats at the bar, soaking in the energy, and watching all the action. We've even met another couple here who've since become friends, that's how welcoming and fun the vibe is. On our most recent visit, we tried a couple of new items. First was a starter: shrimp wrapped in bacon, served on a flat skillet with bell peppers, onions, and a lovely chipotle crema. Absolutely fantastic. The flavors were smoky, savory, and perfectly balanced. We also had the chance to try something from their most recent chef's tasting night, a tuna tostada made with sushi-grade tuna. It came as three tostadas topped with beautifully marinated tuna, and it truly tasted like heaven. It probably won't make it onto the regular menu, which makes me even more grateful we got to experience it while we could. Still one of our favorite spots, and we'll definitely be back (as usual!).

    Also, note the vaulted ceiling!
    Dan L.

    First I have to say I just finished lunch at the Guadalupe on main. The second thing I have to say is I am so full. I probably will not eat for a week. That's a lie, it'll probably be more like 3 or 4 hours. So I was stuck in Arizona getting my car fixed so I was kind of trapped at the hotel with limited food options within walking distance. Of course, I opened up Yelp and found that this place called Guadalupe on main was a literal 5-minute walk from the hotel. I was really craving some Mexican food and was super excited about trying this place out. An easy walk down main Street and there it was on the right hand side. The exterior of the building was very modern and elegant, to be honest I thought I was going to have outpriced myself for lunch. But I was pleasantly surprised when I walked through the door The place is just as elegant on the inside, and when I say elegant I don't mean dressy or overly classy, neat and clean, perfect amount of decor, and a very great open seating area. One of the things that stood out was the giant open window at the far side of the restaurant that had a brick wall going up with this beautiful painted mural on it. Not to mention that there was a green alien skeleton relaxing in there. See my pictures if you don't believe me. I ordered some chips and salsa and a beer, and was not disappointed. Sometimes you never know what you're going to get when it comes to chips and salts at a Mexican restaurant. Best case scenario is that they are homemade. Worst case scenario is they bought them from a grocery store down the street. These were fresh and hot and came with two different kinds of salsas... Red and green. This was especially a nice touch as most places only give you the red sauce. For the main course, I ordered carnitas, if you've read any of my other Mexican restaurant reviews on Yelp, you know that that is The benchmark that I judge a Mexican restaurant by. The carnitas was perfectly cooked, had just the right amount of char on it and was moist and flavorful. The rice and beans were top notch and they gave you a little dab of guacamole on the side to put on your tortillas if you wanted to make a taco. I got to meet the owner, Dirty. Mike, super nice guy, very friendly, made great suggestions and you can tell his heart and soul is in this place. Bottom line? If you are ever are in the Mesa area and looking for some good Mexican food, this is a place you need to add to your list. Everything was phenomenal. And I will definitely be going back again!

    Corn Queso and Chips and Salsa
    Rob M.

    We went for dinner on Friday night at 7:30 pm. Call and make reservations in advance --it was busy! The staff was friendly and perhaps a little short as timing ran slightly long. The interior is one large open room and it was loud and just a touch too bright. The menu offers extensive gluten free options. We ordered the corn Queso, Chips and Salsa, Cheese enchiladas with green sauce, chile relleno, Birria tacos, and steak fajitas. The food was delicious! As luck would have it, we were sitting right next to Van Jones! We will be back.

    Azteca salad--no shrimp
    Crystal Z.

    I saved this place on TikTok to try. We came. We seen. We tried it. Kinda bummed...Let me explain... I ordered the Azteca salad without shrimp. It was good. 7/10 good. Nothing special. The pollo asado--the meat itself was flavorful. The vinaigrette was surprisingly good. My issue was the field greens were full of stems. The portion size was on the smaller size for a salad that was almost 19.00. The fiancé had the asada plate and he rated it a generous 5/10. He said the meat lacked flavor. The refried beans tasted like canned and the rice was dry. He was upset he spent 25.00 when he could have gone to Chipotle for a steak bowl. The chips and salsa were...just chips and salsa. A bit small on the portion size for chips. The red salsa was mostly a tomato base with no spice. The green salsa was the better tasting salsa. The best part of what we ordered were the cocktails. We both enjoyed our drinks. I had the Jackoloupe Cowpoke and the boyfriend ordered the Thirst Trap. We both would rate our cocktails an 8/10. Service was ok--she forgot our straw and never came back around to ask us if we wanted to order another cocktail. We probably would have if she had asked. Overall--first impression was underwhelming and overhyped. The food definitely was not giving authentic Mexican and was very average at best but the cocktails were decent. To drive 15 mins for Mexican food and cocktails there are other options but we can at least say that we tried it.

    Drink menu May 2026
    Mstng O.

    The staff was attentive on a Wednesday night. All of the drinks and entrees were made of quality ingredients. We had the tuna tostadas for an appetizer which featured a delicious spicy sauce. The mole enchiladas tasted like candy without being sweet at all. The lobster chorizo enchiladas were likewise decadent without being overwhelming and the fresh cucumber was the perfect compliment.

    My drink was flaming!!
    Monica S.

    Came upon this place so randomly. I love Mexican food and always am craving a good margarita. Hands down; the best of everything!! A Cadillac marg so good, that is the reason I will go back. A daily special; an Ahi Tuna Tostada. My husband got bacon wrapped shrimp. What words could I use to encourage you to try this place out? Exceptional-Memorable-Repeatable I'll be going back before my vacation ends

    Decor
    Savannah R.

    Okay..WHAT is this hidden gem?! If you haven't been here, stop what you're doing and get over here now. Guadalupe on Main is a Sonoran style Mexican food spot giving off upscale moody upscale vibes. Upon entry, you'll walk around to the main dining room. You will immediately see that moody feel with the dark painted walls & mid century modern furniture. Our server made his way around and was very friendly. We were a group of 8 with small children and he was patient and welcoming with all of us. We started off with chips and salsa, which was nothing to rave about. Once our food hit the table, it was so beautifully and elegantly plated. Everyone enjoyed their food and I especially loved mine. I opted for the chicken mole enchiladas and they were SO GOOD. The mole was as authentic as my grandmothers and each rolled into a handmade corn tortilla and stuffed with just enough filling. For dessert, we had the churros with chocolate and they were served warm and soft. Around the corner from the dining area, you will find a small sports bar and make way your to the secret door for a speak easy! You'd never think it was a door, it is made to lol like a little library! Honestly I think it's a tattoo shop behind there I'm not sure what I was told but it closed unfortunately so we couldn't go. So happy we found this place!

    Pattarawadee K.

    I would give them 5 stars if their chip is not sticky and chewy besides that theirs foods is wonderful

    Ceviche
    Donnelly N.

    Went back and the lighting seemed a bit softer. Restaurant was still a bit echoey. But great service and delicious food. We ordered the potato tacos - listed as an appetizer but it was huge. 3 tacos and could be an entree. I ended up ordering the ceviche appetizer as my entree and also huge! The people I was with ordered enchiladas, chicken fajitas, and carne asada. All enjoyed. And they have homemade corn tortillas that I got to sample. They have someone who just presses tortillas all day!

    Chips and salsa
    Christine B.

    I'd been wanting to visit this restaurant for awhile after seeing the good reviews. We're always down for Mexican food. The service here was very friendly and attentive, starting with the small child who brought us our menus. I think we might have been given complimentary chips and salsa once they found out it was our first visit, which was considerate. (And a smart move - since a lot of people complain about how they charge for this.) I ordered the chicken fajitas and was nothing but pleased with them. Everything was solid: perfectly cooked and seasoned meat, great flour tortillas, tasty beans and rice and a generous portion. Of course it was enough for lunch the next day as well.

    Excellent Flan for desert.
    Art H.

    9/28/25 Second visit. Parking 5/5 Early dinner-4:30 pm. Easy parking on off peak visits in private lot. Atmosphere 5/5 Beautifully done in a modern contemporary Latin design. Service 5/5 We were greeted immediately and offered our choose of table. Our server Mia joined shortly after being seated. We let her know we were ready to order and she did. Very friendly. We ordered iced teas, two Steak Fajitas meals, pan fried jalapeños, two Barria Tacos Ala cart. Mia asked if we'd like to have our tacos first. After dinner we ordered their Flan. Food 5/5 Everything we ordered was Guadalupe delicious! Way too much food so we brought home leftovers for another meal! Entertainment 5/5 We had a DJ for our entertainment He played R & B, it was a nice show. Eat well my friends-SYOY

    dana c.

    This place was wonderful- excellent service, excellent food! The interior is tastefully decorated with motifs to Mexican history and culture that my parents had a fun time pointing out. The food was absolutely delicious as well, and in my mom's words- 100% authentic. As for my thoughts... if you're craving salad, I recommend the Azteca Salad. Delicious and a generous serving! Our server, Gwen, was super nice and very attentive to our table. She elevated our dinner to that 5/5 experience we were looking for. We'll definitely come back here again.

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    1 month ago

    Great food and atmosphere. The best. My wife had us come two nights in a row. You really need to come here. A great date spot.

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    2 days ago

    An amazing locally owned and operated restaurant that makes a point to treat you like family. Food and drinks are top tier.

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    Absolutely amazing food and service!! It's our favorite Mexican restaurant. They also cater to allergies, which is amazing!

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    Page 1 of 7

    The Guadalupe on Main Reviews in Other Languages

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