I've had lunch at Regina's Grocery more times than I can count, and after working my way through the entire menu, I can say confidently: this place is absolutely worth a visit. Regina's isn't just another sandwich shop--it's a deeply personal, family-run Italian deli that feels like stepping into someone's home kitchen. Founded in 2017 on Orchard Street by Roman Grandinetti, the shop pays tribute to the Bensonhurst social clubs and old-school Italian groceries he grew up with. It's named for his mother, Regina, who still makes the sauces and meatballs using family recipes. The walls are lined with vintage family photos, and every sandwich on the menu is named after a real relative--"Uncle Jimmy," "Grandma Lucy," "Uncle John." That sense of family is the whole heart of the place. As for the food? Consistently excellent. The ingredients are fresh, the flavors bright, and the portions generous. My personal go-tos are the Uncle Jimmy--stacked with prosciutto, hot sopressata, smoked ham, fresh mozz, roasted peppers, and their addictive chili spread--and the Meatball Parm, which is one of the best in the city when it's on special. The Uncle John is another classic that really shows off the quality of their meats. Yes, the prices run a little high, but the overall quality and care that go into these sandwiches make it feel justified. Service is always quick, friendly, and genuinely welcoming--no attitude, no fuss. The space itself is small and no-frills, exactly what you expect and want from a Lower East Side Italian deli. If you love Italian sandwiches made with care, heritage, and great ingredients, Regina's Grocery is a must. I keep coming back--and I always leave happy. read more

A perfect lunch after an afternoon of archery. They only do chicken parm on weekends so as soon as he mentioned that we were sold. Sat at the window table watching it rain and stuffing our faces. One of the best I've ever had. Very attentive and genuinely kind staff. read more

Regina's Grocery - Chicken parm - Italian Near Me - New York, New York

Great sandwiches and cannolis. The Jimmy is great with fresh bread. They are available for delivery or walk in.

Flavorful and fresh sandwich shop. Tried the Uncle Jimmy, which was packed with prosciutto, mozzarella, roasted sweet peppers, balsamic, and arugula. The sandwich was large, a bit pricey, and very shareable. I'' glad I tried it, though it's not my sandwich of choice as the flavors can be a bit overwhelming (my boyfriend says it's his favorite though!) Service was fast and friendly, and this location is very cute / ambient but does not have a lot of seating. read more

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The Uncle Jimmy's was great flavor wise and I wasn't sure if it was me.. but my jaw was just tired of chewing after eating half the sandwich. Will save some money next time I'm here as the full sub is too much of a mouth workout. $20 is a hefty price to pay anyways for lunch in the area... Lots of cheaper options. read more

Ordered delivery to the office for lunch. Uncle Jimmy was really good, though the bread could be better (better at Alidoro). Great Italian sandwich option! read more

Regina's Grocery - Uncle Jimmy - Italian Near Me - New York, New York

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Small Italian grocery in Chinatown serving up huge tasting sandwiches. Laid back establishment with cool staff. Buy a sandwich and take a load off dining in. My go to is "uncle john" but every sandwich is a great choice. read more

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Small little charming spot in LES. This place is simple and exactly what we were looking for. The ambience and the sandwiches have so much culture and identity to it! We were looking for a true italian sandwich and Regina's definitely hit the spot. All the different meats stood out individually but came together to perfection. Most sub places these days are overwhelmed by oil and vinegar, but Regina's definitely lets their ingredients shine. Definitely stop by if you have a sandwich craving! read more

Regina's Grocery - Uncle John - Italian Near Me - New York, New York

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wow better than any other Italian sub I have had. I added the ham and sun dried tomatoes but wow. read more

Regina's Grocery - Uncle Jimmy - Italian Near Me - New York, New York

Sandwich was large and filling with great ratios, great service and when I was finished, he came and gave me a piece of pannatone

Long overdue review. Worth checking out if you're in the city and you like sandwiches, especially Italian sandwiches. No frills place. It's tiny - basically just order at the counter. There isn't really seating inside, just a two topper outside. There wasn't a line when I went, but it took awhile to get our order because they prioritized pick up / delivery orders. I got the Uncle Jimmy without the hot pepper spread because I can't do spicy. The other person I was with got the same, but with the spread. Sandwiches didn't come with as much meat as some other spots and we did ask for extra balsamic, but overall it was good. Crunchy bread and fresh ingredients! read more

Regina's Grocery - Uncle Jimmy Sandwich - Italian Near Me - New York, New York

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Not a warm welcome would be an understatement. It felt like a bother to even be there. When I asked if they were doing the muffaletta (which was on Instagram) and was told "No," I replied that I was really sad not to be able to get it. I was then met with a response along the lines of, "When were you even here when that was here?" Just awkward. I went for the Uncle John. It was pretty much flavorless. No zing, no seasoning, nothing. For a lunch that cost over $50 for two sandwiches, two cokes, and a bag of chips, I was super disappointed. I'll give a star for the location and a star for the fact that they had a table inside to sit and eat, but I won't be back. read more

Stopped by because I saw it was ranked #1 on Beli for Italian Sandwiches in NYC. Don't think it quite lived up to the title, but they were good sandwiches all the same. Quite expensive for their size though, I expected a bit more out of an almost $20 sandwich. We got the Uncle John and Roman to split between two people and finished everything. I thought I would like the Roman more since I like pesto (nut-free!), but surprisingly the Uncle John came out on top. The hero was softer and fluffier bread, and I enjoyed the three different deli meats. The smoked chicken was good in the Roman, but not as flavorful and the stirato bread was a bit hard. Both sandwiches were just lacking a bit in the sauce/flavor department, I could've used some extra pesto in the Roman and more of the roasted red peppers on both. read more

Regina's Grocery - The Roman Sandwich - Italian Near Me - New York, New York

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I love the sandwich options they have here, they all sound delicious. I got the Uncle Jimmy sandwich which had some heat to it from the hot pepper spread which balanced well with the mozzarella. It's definitely very pricey for the size of the sandwich ($20), but delicious. Service was extremely fast for a takeout order. Cute decor inside! read more

Regina's Grocery - Uncle Jimmy Sandwich - Italian Near Me - New York, New York

Picked up the Uncle Jimmy before a Rockaway beach day and wow -- I was so impressed by this sandwich. The Uncle Jimmy had just the right amount of spice and a great amount of prosciutto and hot soppressata. The flavors just went together perfectly. The bread was slightly tough, but still really good. The sandwiches are definitely big enough to share (which helps justify the $18 price tag). I'll definitely be back for more! read more

Regina's Grocery - Uncle Jimmy Sandwich - Italian Near Me - New York, New York

This place has amazing sandwich's I've been getting delivery from them for about a year now. Everything is super fresh big portions and it's one of the best sandwich places around. read more

I came across TikTok reviews praising this place. I tried the uncle jimmy sandwich, but it arrived cold, which was disappointing since I prefer warm sandwiches. The flavors were okay, but nothing exceptional. The prices seemed too high for what you get. read more

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This is the type of establishment that makes the LES the LES and makes NYC so special. Historic, family owned, and familiar in a warm way even when you first walk in. Even if you don't like the sandwich (which you 100% will) you'll taste the love and it will keep you coming back for more. Do not walk by without giving it a try. read more

Amazing sandwich! The deli meat was so yummy, and the bread was perfect texture too. The peppers that came with my sandwich were so flavourful and mixed super well with the meat. Highly recommend read more

I ordered a meatball parm and an Uncle John after seeing a film at Metrograph. I ate half and half. The meatball parm was big and honestly pretty great. I would order again. The Uncle John was what the cashier recommended when I asked for the "most classic Italian sandwich" and it was good but could have used more vinegar. I had to add more at home. The ambiance is why I walked in. Looked super cute and was but no other customers were inside. Employees were super nice. I would go back. read more

Delicious ass sandwich. Exactly what you want when you see photos and it tastes better then expected. Nice overall vibe. Service was quick and sweet. read more

Regina's Grocery - Uncle Jimmy Sandwich - Italian Near Me - New York, New York

Some of our favorite subs! So many delicious sandwich options and such a fun vibe. Uncle Jimmy and Uncle John are the best! read more

Regina's Grocery - Italian Near Me - New York, New York

Another solid sub place - try the uncle jimmy!! Fast service and nice staff, get it to go! read more

Regina's Grocery - Cousin Uncle Jimmy Sandwich - Italian Near Me - New York, New York

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Incredible sandwiches. First visit, we got the Uncle Jimmy and a meatball parm. The Uncle Jimmy was fantastic, and the bread it comes on is about as good as it gets. The meatball parm was the real star for me -- maybe the best version of this sandwich that I've ever had. We'll definitely be back to try more. read more

Regina's Grocery - Meatball parm - Italian Near Me - New York, New York

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I had the eggplant parmesan hero. It was a large portion with plenty of cheese and buttery eggplant, with plenty of sauce and bold garlicky flavor. The bread did get a bit soggy by the end, but that wasn't a huge deal. Another minor annoyance is that the cheese got really stuck to the wax paper and was hard to get off. Though the flavors are good, I'm not sure $19 for the sandwich was really worth it. read more

Uncle Jimmy hit the spot! Hey, if that line for Scarr's pizza be down the block, you best bet I'm opting for a sandwich at Regina's. Even standalone, it's a solid sandwich & there's minimal wait. Props to the guys filling orders quickly while being so chill & friendly! read more

Regina's Grocery - Menu - Italian Near Me - New York, New York

So delicious! Sandwich's are incredible and the staff are friendly! The cashier in overalls is such a gem! Totally recommend!

Kitschy and uniquely decorated grocery store that serves the best Italian sandwiches! The bread is freshly baked and the meats are perfectly aged and flavorful. Their mozzarella tastes the best out of all the Italian restaurants I've ever been to - perfectly textured & just so mild and creamy. Their hot sandwich specials are to die for - the chicken Parmesan was made with homemade tomato sauce and a huge slab of their delicious mozzarella, melted to perfection. The service was perfect - we sat outside to enjoy the fall day and the attendant brought our sandwiches and drinks out to us. Honestly the PERFECT place to be transcended to Italy with dope NYC flair. Can't wait to go back. read more

This place is hands down authentic Italian food the place to get a sub. To start, the people, the service, was super friendly. Nice people. Definitely a hole in the wall but trust the process. As we walked in someone was boasting about how good the chicken cutlet sandwich was. Both my friend and I's food was hands down amazing. So fresh and I even ate the other half 4 hours later, unrefrigerated, and through the pouring rain and it was still perfect. I will be returning, and you should be going!! read more

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The Italian-American family owned vibes at @reginasgrocery is so cute! They have a couple seats for a cozy indoor dining experience. The mozzarella was fresh and my first bite already reminds me so much of Italy read more

This cozy little Italian grocery and sandwich shop's decor suggests it's been around much longer than its 3 years of existence. Maybe it's the black and white floral tile floor or that the owner takes orders and yells them back at his ma, who makes all the sandwiches. It's a very New York place with very New York flavors. Take the Uncle Rocco, which is a classic tuna sandwich you'd find at any classic Italian deli only made even better with their own pepper paste, fresh mozzarella, broccoli rabe, arugula, balsamic, and extra virgin olive oil on a classic hero. The bread is exceptionally fresh, and the sandwich is simultaneously tart, savory, and earthy. It's my favorite on their menu. They don't always have tuna, so sometimes getting the Uncle Rocco is out of the question. While at most sandwich shops, pescatarians and vegetarians would simply be out of luck lest they want a mediocre meal, Regina's comes to the rescue with veg friendly options aplenty. I'd point a meat-free seeking patron to the Cousin Steven, which has eggplant, zucchini, mozzarella, celery, capers, and arugula on a classic hero. Gotta get your sandwich on a classic hero, it's the best. There will likely be a little wait to get your sandwich, particularly during peak times as it's a very small team preparing each item, but I promise your meal will be that much more satisfying. Buon appetito. read more

Regina's Grocery - Uncle Rocco sandwich - Italian Near Me - New York, New York

I'm so glad someone told me about this place! They said they have great sandwiches, and they truly do. I had the Uncle Jimmy, and it was all that. It's a whole in the wall with cool people taking care of you, Lower Eastside style, just how it should be. Love it. read more

Regina's Grocery - Uncle Jimmy - Italian Near Me - New York, New York

Regina's is a "window" order sub sandwich store with outside eating across the street. My bread on the special "Johnny" was hard but the inner meats, sauce and veggies were delicious. My hubby's sandwich came on chiabatta bread and olive spread which was tasty. Dispute the delicious meats I give 3 * due to the tough bread and expensive prices. read more

Regina's Grocery - Regina's hero sammies - Italian Near Me - New York, New York

Regina's grocery had been on my hit list for years. I finally made the trip over a couple nights ago to grab sandwiches for a train ride upstate. The service was amazing, and the sandwiches were being wrapped up at the exact time I came in minutes before they closed at 6 PM. We opted for the Uncle chubby, Uncle Jimmy, and Cousin Cristina. We all sampled each other sandwiches and they were all delicious, but I'd have to say the clear winner would be the uncle Jimmy. We also got it on the semolina roll which made the sandwich about twice the size. I think the key at Regina's grocery is the spicy pepper spread - any sandwich with that cannot not be good. I'm looking forward to returning to Regina's grocery to try some more of their sandwich selections. You really can't beat charcuterie cold cuts on crusty fresh bread. read more

Regina's Grocery - Uncle Chubby Sandwich - Italian Near Me - New York, New York

This spot makes some delicious Italian style sandwiches & subs. I usually order the uncle chubby which has spicy sopressata, fresh mozzarella, peppers, & balsamic. I loved how fresh all of the ingredients were & the bread is fantastic - perfectly chewy and crisp. They have a small selection of snacks & drinks too - it's an ideal spot to stop by for a quick lunch on the go. read more

Stopped by before our flight to grab 2 hero's because I had to be better than airplane food and was the right move. Everyone on the plane was jealous when we pulled out these masterpieces. read more

Regina's Grocery - Elevated airplane food - Italian Near Me - New York, New York

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Sandwich was still great. Happy they were open today on the holiday. I enjoyed an Uncle John hero. Delish.

Super cute place. Homey and nice. I got the Ricky sandwich and it was very yummy. Service was great. I enjoyed the jazz music.

I had a meatball parm hero, a special of the day, and sat at a small table in what you would consider a typical NYC shop from the 1940's, with black and white ceramic tile floors and a pressed tin ceiling. I was bathed in the soft reggae music and enjoyed my free chocolate cake dessert when I checked in on Yelp ( surprisingly good pre-packaged and imported from Italy). The quaint air-conditioned setting and the attentive friendly service is just what I needed on a hot summer day. read more

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Mozzarella dry as feta, bread was stale even though it was 12pm on a Friday, type of place hyped up by tourists and people that enjoy paying $20 for trash, learn how to slice prosciutto not supposed to be as thick as the bread read more