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La Santisima

4.2 (2.7k reviews)

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LA SANTISIMA ATMOSPHERE

What's the vibe?
Moderate noise
Casual
Classy
Good for groups

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Recommended Reviews - La Santisima

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Reviews With Photos

Daniel R.

Mexican food so good that I want to move to Phoenix! Visiting from Southern California, I was curious to see how Phoenix mexican food compares and I was absolutely impressed. Approaching the restaurant, you'd think it was a night club as you pulled up. As you enter through a huge swinging door, you are welcomes by spanish music, walls plastered with art and dozens of hanging wood lights with warm led bulbs. You'll be welcomed with a drink menu, a regular menu, and veggie/vegan menu as well as a basket of freshly fried chips. As you wonder where the salsa is, you'll look over and notice that there is a dedicated salsa bar with 18 different salsa options! I tried most of them and my wife and I absolutely loved the classic Pico De Gallo and Guacamole Sauce. For our entree, we opted for the Quesa with Al Pastor, enchilada style. It was an absolute experience and a unique fusion of an empanada, tamale and taco! The service was great. Our waitress was sweet and had great menu recommendations. The bar has unique swing seats. Since it wasn't busy, they were accommodating to let my 3 year old enjoy some swing time. We highly recommend coming to La Santisma!

Street taco and rice, no garnish.
Catherine H.

La Santisima. This is one of the top two places I send people when they ask about good Mexican. When my husband and I first moved in together some 14 years ago, this place was called La Condesa, and it was a quick walk from our house. It was a tiny shop with unbelievable quesadillas and a salsa bar that took up nearly a quarter of the dining area square footage. It changed names, not owners or recipes. It grew in fame, and space, and they added more decor. Then they moved to a bigger, much trendier location, but they've always stayed true to their vibe and their cuisine. Coming here has always felt like going home. Get the chips, the guac, the tacos, the quesas, visit the salsa bar 100 times, try a cocktail or stick to their unique horchata. You truly can't go wrong here. It's remained one of the best Mexican places the valley has to offer, and I hope it stays around for years to come.

Matthew C.

Not gonna lie, I had no idea why this place was this hyped up on Reddit. Food was alright, but everything was just crazy style expensive. Honestly, the free chips were the best part of the meal. Maybe there was something else on the menu that everyone else goes crazy for but for me it was just pretty run of the mill. Kudos for the large salsa bar tho, so many different ones to try, that was genuinely pretty cool.

Decor!
Andrew L.

Fully stoked I finally tried this place on a trip to phoenix. Probably the best fish taco I've ever had. Everything was really great. The art and ambiance were spectacular! And my server was busy but very nice. Total A+

Dining Room
Pete M.

Friends, La Santisima is the SPOT!! Amazing ambiance, great food, great salsa bar. Many different flavors, options, and sauces. The Menu here is huge, see pictures!!!! Jenny our server is amazing and customer focused, making sure everything is perfect. Will definitely return, super impressed!!! Grade: A+++

Mole Taxco Pink Mole Taco, Baja Sur Shark Taco, Jamaica Rose Shrimp Taco, Arabe Al Pastor Taco
Tiana E.

Super cute spot with unique tacos! The decor is really cool too. The guac was amazing, it has cranberries in it which were a surprisingly delicious complement. We had the shark meat taco, the Arabic style taco, a very unique but good shrimp taco with Jamaica salsa, and a mole taco. All were phenomenal!

Erin D.

I haven't been to this place in probably 10 years since it was a tiny little restaurant in a strip mall. I loved it then and decided to come for lunch and was pleasantly air at both the new location and the upgraded menu. The ambiance is amazing - between the art and the swing seat at the bar. I love the vibe And the menu has been expanded with a ton of really cool Mexican inspired tacos and food that are really unique. They even have a separate vegan/vegetarian menu. The tacos we ordered were all flavorful and the meat was perfectly cooked. Shark tacos, mole-based tacos, Argentinian beef. So many interesting combinations. And best of all, they still have the amazing salsa bar that I remembered. Lots of good spicy options if you like it hot like I do. And last but not least, service was friendly and efficient. Still love this place, and maybe even more than I used to.

Photo
Rachel V.

This place had really good reviews and we wanted an authentic AZ experience. Pluses- definitely the decor. 5 stars! Super cool dia de los muertos motif. The guac was really good and I liked the salsa bar. I didn't like the carne asada taco. It really was disappointing. The shrimp taco was quite tasty. Really liked the beans and rice but the portion was rather small. The menu is really overwhelming and I think if they rewrote it/ basically said these are all the options but you can have them as tacos, burros, etc it would be easier to follow. It's literally the longest menu I've ever seen! Also there was only one waitress so it took kind of a while to get things. Overall positive experience but some things could be better.

Mark S.

I have eaten here only once so far. I'll definitely be back. This restaurant has some amazingly good food. The black mole tacos are to die for...but I'm getting ahead of myself. The ambience is interesting. I'm not sure how to describe it. I encourage you to check it out yourself. We had great service. Our server was friendly and attentive. I'm not a tequila drinker so I can only say that the list of tequilas they serve is impressive. Back to the food. It was all very tasty. I highly recommend giving La Santisima a visit.

Bar
Chris A.

Great place, great decor, food is incredible. Service was ok. The menu is frankly overwhelming lol- Never seen so many options! Will be back next year

Brandon P.

Found a decent Mexican spot! Great service and a nice atmosphere. The guacamole was flavorful and delicious. It wasn't too much where we could get full too :) The chicken bowl mole was rich and smokey with just the right amount of spice. The asada taco was cooked perfectly and well seasoned. The Mahi Mahi Santisima Special taco was delicious!! The beans and rice were also delicious. The only disappointing things we had was the Margaritas and the salsa bar. The Tamarin lacked any real flavor and they both were pretty weak. The cups were tiny and really couldn't get any salsa.

Shrimp and mariachi loco tacos.
Jenn W.

Love this place. Hadn't been in a minute and the menu has expanded. The motif is great. Our wait staff was perfect with great recommendations. I had two tacos - I always get the shrimp, which is my favorite- and added a new one. Don't skip on the horchata- it's my fave in the valley. Cool joint, great art work. The bar has swings. I mean, what more do you want?

Cazuela

This was honestly one of the most disappointing dining experiences I've ever had....ive never and I mean NEVER have not finished a plate at a restaurant. I was served a COLD dish with 3 pieces of chicken, 3 pieces of chili and a BUNCH of beans and rice smothered in a god awful white cream sauce.....definitely won't be coming back. The only good thing about this meal was the agua de horchata....that was pretty good!

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10 months ago

This place has the absolute best tacos in the valley. Their flavor is so dialed in and the service is amazing! You won't regret a meal here

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11 months ago

Whenever we talk about Mexican food we always go back to La Santisima. We enjoyed our meals so much we will come back again and again.

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La Santisima Reviews in Other Languages

Ask the Community - La Santisima

Do you have a vegan menu?

Yes www.lasantisimagourmet.com

Is there a happy hour?

Daily Happy Hour 3:00 PM - 6:00 PM (Daily) Buy 2 gourmet tacos - get $5 off… Read more

Did/do you have an Al pastor taco that has hummus or tzatziki in it, like a cross between a taco and gyro?

Yes is the árabe

Are reservations offered?

Yes

Tried to go to lunch today since it was listed as open, but it looks like the business is still closed. When will this location open?

We are planing to open our new location 4117 N 16th st Phoenix az around 3 weeks but you can visit our Glendale location 5932 W Glendale Ave. Glendale, Az thank you!!!

Is the Phoenix 16th Street location open?!! We have been patiently waiting for months! The Glendale is a bit of a hike for us.

Yes! And it's super cute.

I noticed that yelp has this business listed as open. We tried to have dinner there last night and they are definitely closed. Our friend arrived first and was told they are closed for repairs. Does anyone know when they will reopen?

We are still working on repairs our Glendale location is open ETA 3 weeks apologize any inconvenience . Thank you!!!

Did they close?

There is another thread with this question. The owner responded that they are still doing repairs and will be open in a couple of weeks. So, maybe check by end of the month.

Did they close for good? Drove by the other day and saw it was boarded up- I went not that long ago! I'm so sad !

Hey we are almost done with the repair s we will be open in 2 weeks thanks for your support our Glendale location is open

Did this restaurant close down indefinitely?

I drove by in March and it just looked like it was closed temporarily. Then again first week of April and now it's boarded up! It's a shame, this place had really good food and drinks - but the interior was needing rehab and the service was really… Read more

Is the 16th street location open? I went by on 3-28-21 and the building looked closed.

I just called the Glendale location and they said they plan to open it back up in a month. Hope they have been working on it as the interior was needing some help.

Are you offering dine in currently?

Yes

Hi friends! Are you open for takeout during the stay at home order?

Yes from 12pm thru 8pm

What happened to Joel? He no longer works here, we're gonna miss him.

We missed him but unfortunately he was taking picture of our recipes apparently to share to the competition :(

Are they open on Thanksgiving?

Thursday we are closed

How late is breakfast served?

12 on weekends

Is there breakfast now?? Where's the breakfast menu?

There is breakfast now! At least on weekends, I have not tried during the week. The menu is provided when you get there, its kind of a new thing so I don't think they have it in a digital format yet.

Don’t See Your Question? Ask Away!

Tacos Veganos - 3 tacos with asada

Tacos Veganos

(322 reviews)

$$

Here's the updated version:…read more Tacos Vegonos is hands down the best vegan Mexican spot I've found, and I'm picky! Growing up on San Diego taco shop street food, I have a high bar for Mexican food, and this place hits home in a way nothing else around here does. The selection is unbeatable -- there's literally nothing on the menu that isn't good! I used to eat here one to three times a week. My work schedule changed and now it kills me that I can't get out as often, since they're in central Phoenix and I'm out in far East Gilbert. But trust me -- this place is absolutely worth the drive. The birria is my go-to on anything, and I'll often do a 50/50 split on the nachos or the fries -- both are killer! I remember when they were just a taco truck, and the food was amazing then too. Moving to a brick-and-mortar didn't change a thing -- same incredible quality, same fantastic customer service every single visit. Worth your money and worth the trip, even if you're not vegan! It may not be the healthiest ingredients, but the flavor more than makes up for it. Go taste it for yourself -- you won't regret it! Want me to tweak anything else?

I just had food delivered to my hotel and I feel bad because I think I got someone else's nacho…read moresauce in my order! I got the massive Arizona burrito with birria and it's delicious! I also took advantage of the special taco plate and got two chicken and one asada. Also so delicious! Both salsas were also really tasty. I really wanted to try the birria ramen especially after reading another yelper say the noodles were good. I'll have to wait until the next time I'm back in Phoenix. Btw, the nacho sauce is really tasty!

La Santisima - mexican - Updated May 2026

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