If you're even thinking about going to Two Sisters Creole Kitchen, stop thinking and just go. From the moment we walked in, the staff was absolutely amazing, welcoming, attentive, and genuinely friendly. You can tell they take pride in both their service and their food. The energy was warm, authentic, and felt like family. Now let's talk about the food... straight bomb dot com. The fried oysters were perfectly seasoned and crispy on the outside while still tender and juicy inside. The red beans were rich, flavorful, and tasted like they'd been simmering all day the way they're supposed to. And the fried catfish? Golden, crispy perfection with flaky, melt-in-your-mouth goodness. Every bite had that authentic Creole flavor that hits your soul. This isn't just a meal, it's an experience. We'll definitely be back. Highly recommend! read more

Two Sisters Creole Kitchen - Cup of Gumbo, macaroni and cheese, fried oysters - Seafood Markets Near Me - Picayune, Mississippi

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I've been going here since I moved up to the Picayune area in 2026. Excellent food and great service. Definitely a return customer!

Great food, exceptional customer service, and down-home ambiance. I'm a fan of the Thursday special: butter beans and rice, with a grilled pork chop, and corn bread. You have three choices for the pork chop: grilled, fried, or stewed. read more

The service was good. The menu well versed, something for everyone. The food was good. The restaurant was old school but well taken care of. We noticed many improvements to the building. read more

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We had the jambalaya with a crab cake and the fried shrimp rollup with sweet potato fries. Both were delicious and really inexpensive. The place was busy but the service was great and kind to a couple of tourists. Prices are really low for the quality and quantity. This is a classic small town restaurant run by people who care about the food and the customers. read more

Large menu, lots of choices. Family atmosphere , most tables seemed to be regulars. Friendly fast service. We had plates of fried oysters with red beans and rice and cornbread. All tasty and well done. Well worth a detour off the highway. read more

Two Sisters Creole Kitchen - Fried oysters with red beans and rice - Seafood Markets Near Me - Picayune, Mississippi

Wow! This place is great! The menu has plenty of options that are all priced at low prices! The service was fast and very friendly. The inside has plenty of room with lots of tables to sit at. Everything was clean and well kept! This is a must go place if you're in the Picayune area! read more

Two Sisters Creole Kitchen - BlackBerry Cobbler - Seafood Markets Near Me - Picayune, Mississippi

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Honestly the worst dining experience I've had in the past 10 years. Food took 30 minutes to come out, and it was undercooked and the fries were soggy. When I tried to ask for a refund the cashier rudely told me that's not possible although I was not happy with the food nor the service. Was overcharged and overall a terrible experience. I wish I had better words to say about this business. read more

My brother and I were traveling to Baton Rouge and found this gem. It's delicious and as far as I can tell, super authentic- they've been there for at least 30 years! I even ran into a woman a bit later working at a gas station and mentioned the food/ place and she lit up and said how much she loves it and worked there for 4 years. We had the jambalaya, gumbo, boudin; and crab cakes- again- a must go! read more

Two Sisters Creole Kitchen - Seafood Markets Near Me - Picayune, Mississippi

Maybe we came on a bad day, but food was average at best. The crab cakes were decent but were much too salty. Got the boudin balls as an appetizer and they were very plain tasting. My wife's shrimp was very tiny and the sweet potato fries were way too salty. I was real disappointed as were heard they were good. Maybe we will try them again on another day. read more

What a great place to eat. Large portions and great staff. I had the red beans and rice with a fried pork chop that was huge and my husband got the special crab cake Monica with jambalaya. We both made our selfs sick eating because it was so good we couldn't stop. Tiffany was our server and she was great. Will definitely be back. Can't wait to try something new. read more

Lunchtime and you're in Picayune, Mississippi, where to go ? I check out YELP and found that Two Sisters came highly recommended. A couple of rules I go by while traveling is: 1. No fast food 2. Eat at a place you never have before Two Sisters sounded good and met both of the above requirements I started off with a good green salad with honey mustard, then a great cup of chicken/sausage gumbo!!! Fried pork chop and red beans and rice was the main course. Everything was great. I hate saying this, but that was too much food. Yes good, but probably enough for two meals. You definitely will not leave hungry!!! I liked the atmosphere, nothing fancy, just good ole cooking and great service! When in Picayune, give them a try. Go get Full read more

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Can't judge a book by its cover! Dang good food! Great service and good ambiance . The food was made fast. read more

Red beans and rice with fried chicken!! (With really soft cornbread. I would love to stop by again if I find myself in Mississippi again :D read more

Two Sisters Creole Kitchen - Red beans and rice with fried chicken & cornbread - Seafood Markets Near Me - Picayune, Mississippi

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So what this place lacks in flare the sister's make up for in quality and service. If you get within 30 miles of this classic dive you have to go. I was there with three other coworkers for lunch. Two of us have the smothered catfish special and two of us had the red beans and rice special. Holy smokes, tons of food and tasted awesome! I needed a nap in the parking lot afterwards. Highly recommend! read more

Everything was good i had a shrimp Po Boy & it was well seasoned , fresh & hot. I liked the service and the pro ppl.

Don't waste your time or money on this slop. Got the mega seafood platter and was highly disappointed. Nothing was mega or tasty about it. I'm sure had I'd salt and peppered the paper napkin, it would have had more flavor. read more

Disappointed there was no DR PEPPER! Great food and service. Recommend the restaurant.

Excellent Creole home cooking with great service. If you're in Picayune this is where I'd recommend eating. Large menu but ask for the special of the day. Warm blackberry cobbler was a great finish to my meal of butter beans, rice and smothered pork chop with a side of cornbread. read more

This place is amazing! It's probably the best place in Picayune to eat. It's really good and super cheap. I currently live in Orlando and I'm use to paying $12+ per dish. I got all this for $8! read more

Two Sisters Creole Kitchen - Seafood Markets Near Me - Picayune, Mississippi

I like 2 sisters but Picayune has some amazing places to eat and there are a few that beat out 2 sisters. Their beans are great, mac and cheese is scrumptious, and small pecan pies are outta this world. I do not like fake crab and the catfish stella is loaded with it (ugh). That is what lowered my score. read more

Friendly staff and quick and delicious food. We just needed a small snack. I ordered a cup of gumbo and my boyfriend ordered a shrimp po' boy. Both were yummy and reasonably priced. read more

Great crab cakes Stella. I didn't even know what Stella was but left loving it! Generous plate of very flavorful seafood with rice. Well worth leaving the interstate for the short drive over to this place. I will stop in again. read more

Great food and excellent service by Mary Ann! I was expecting it to be slow service b/c it was super crowded but quite the opposite!! Joe and I shared the special, which was red beans and rice with your choice of several meats of which we chose a fried pork chop! I ordered crab cake appetizer which was served in a cream sauce, which was good too but the cakes were yummy plain as well. The beans and rice were "ok" but I make better haha! The pork chop was great!! It was really thick and was fried perfectly! Looking forward to coming back one day to try something else on their menu!! Yum!! The atmosphere was a little lacking but food was yummy enough to make up for that! read more

Two Sisters Creole Kitchen - Crab cake appetizer had 2 generous sized cake with a yummy sauce! And the Red bean &a rice with fried pork chop! - Seafood Markets Near Me - Picayune, Mississippi

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Just had smothered chuck roast over rice with corn and corn bread. Wonderful. Friendly employees. Attentive waitress. Fair prices. read more

Two Sisters Creole Kitchen - a plate of food - Seafood Markets Near Me - Picayune, Mississippi

Great food. Lots of flavor. Fast and friendly service. They make you feel very welcome.

Love it specially the gumbo and red beans and rice. They are very professional and family oriented! It's clean and they get your order correct. I recommend this to everyone! read more

I got the red beans & rice and smoked sausage with a salad. My salad was literally lettuce and dressing, but honestly I didn't mind because I love lettuce ‍ I absolutely loved the sausage. I would like to try some other things on the menu. read more

If salt is one of your food groups, you'll love two sisters. I had the special....meatloaf with mashed potatoes and corn. I've never wanted to succumb to a coma more than now. That said, the meatloaf was good. Oily. But good. Then again, I'm in Picayune Mississippi. How do people grow old here? Everything is fried or cooked in trans lard. If you find yourself in this town, shoot yourself in the head. Or eat here. You can't go wrong either way... read more

Can always be relied on for a good meal. Ive had several meals there. I love the butter beans over rice with a pork chop

Food was great. Ordered something interesting called the Stella which is a crawfish and crab cream sauce over jambalaya. read more

Two Sisters Creole Kitchen - Crab Cake Stella - Jambalaya with a crawfish and crabmeat cream sauce - Seafood Markets Near Me - Picayune, Mississippi

This is a no-frills diner, but the food is excellent. I had the crab cakes Stella and the sauce was delicious. It has just the right amount of spice. Everything everyone else ordered also looked good. I would definitely go back. read more

This is a lotta bang for your buck! I came in around 2 in the afternoon and the place was almost empty, but there were several staff so in guessing I just missed the lunch rush. They serve classic southern/Cajun food. I had the Catfish Stella. It was yummy! My bill was only $8 for a whole huge plate of good grub! Not a lot of ambiance to this place, but it is great food for great value! read more

I was driving to Jackson from NOLA and was passing through Picayune. I had missed lunch so I pulled up Yelp to see if there was any good options. Lucky for me I found this place, it was amazing. I wish I lived closer because I'd eat here all the time. I had the Crabcakes Stella and I'd eat it again for dinner tonight if I could. If I'm ever near the area, I'm making sure I eat here again! read more

Came for lunch and was not disappointed. I had the Fried Pork Chop with rice and gravy ... perfection! Hubby had the Catfish Stella ... excellent! I ordered a personal sized Homemade Pecan Pie and it was so worth it. read more

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This place had a busy Lunch crowd,good zign. THE WAITRESS was friendly n courteous. MY Butterbeans n Fried Pork chop was great , tasty, served hot. The Side of Mac n cheese was large n Delicious. THE CATFISH SUGAR BLASTERS w/ Stirfry Veg. Was plentiful but a lil too much Creole seasoning. The Red Beans w/ Catfish was good but catfish serving skimpy,should have received more...however it was good. read more

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Tried this place twice. Pretty good to me...Both times were to go orders at around 1100 their opening time... I had a shrimp po boy dressed with fries once and the other time I ordered a roast beef po boy dressed with a side of red beans and rice with cornbread. Pretty delicious food to me. read more

Two Sisters Creole Kitchen - Seafood Markets Near Me - Picayune, Mississippi

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I was very disappointed I ordered a gumbo and it tasted more like a chicken noodle soup red beans and rice nasty and the green tomatoes weren't fresh they fish was okay though read more

you will never have a better creamy pasta. the catfish stella over pasta is my FAVORITE. the stella sauce is their famous mushroom cream sauce. it could go on anything. 10/10. best restaurant for MILES. sorry i can't find any pics right now read more

Stopped for a night in Picayune, MS and stopped in on a whim. WOW! Great food! I had the crab cake Stella and a side of jambalaya. The crawfish and shrimp sauce/gravy on the crab cake was super, super tasty and the jambalaya was loaded with meat and nicely spiced. My wife had the crab and shrimp combo and it was great also. The place is small and plain but super clean. There were diners in the restaurant and they did a bunch of take-out while we were there so we were surprised to learn that they close at 6:30. Get there early, you won't regret it. read more