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    Santee Seafood Bistro

    4.1 (124 reviews)
    Closed 11:30 am - 8:30 pm
    Updated 3 months ago

    Santee Seafood Bistro Photos

    Business Info

    SANTEE SEAFOOD BISTRO ATMOSPHERE

    What's the vibe?
    Moderate noise
    Casual
    Good for kids

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    Bob B.

    Santee, SC is Our favorite stopover place as we travel Florida - North Carolina several times a year: Nice hotels and several good restaurants. If you're in the mood for Seafood, we really like Santee Seafood Bistro - it's a block off of the main thoroughfare on a quiet street. They also have chicken, ribs, pulled port, brisket. The place is cordial, comfortable and welcoming. Wait staff is knowledgeable and friendly. The same goes for the cook who brings out your meal (a nice touch). I'm a beer guy (nice selection), but I think they have wine and mixed drinks too.

    Savory rich catfish stew in tomato broth over rice. Yum!
    Rich S.

    The Santee Seafood Bistro is a real find, especially if you crave catfish! It's a bright little standalone building just a couple of turns off I-95 at exit 96 onto Old Number Six Highway (SC-6), on Bass Dr at the end of Britain St. There's enough parking to the side and around back. There's outdoor seating on the north side, but it was a little chilly for that in Dec (2024). With a counter up front and tables to the left, there's plenty of seating for the size of the place. The hostess was welcoming and attentive, and the other guests were also friendly to us travelers. We came here for the hot fresh crispy fried whole bone-in catfish, and it was perfectly cooked in a simple light cornmeal salt and pepper breading just like we always had growing up. They also make a savory catfish stew in a rich tomato broth over rice. We were so full, but we did save just enough room for their fresh hot cobbler to finish. Get off that wearisome highway and enjoy some good regular comfort food in a bright place with nice people.

    Fried Seafood Platter
    Joshua R.

    If you want good seafood and friendly service you need to come here! We came in from a long day on the road and felt like we arrived home. The staff were very nice and we were able to get seated right away. They have a wide variety of seafood and bbq options. We ordered the fried seafood platter with a side of okra and the shrimp & grits with a side of collard greens. The seafood was very fresh and tasted great! The amount of food you get for the price is just right! Everything was very good and I highly recommend the collard greens!

    Inside

    As an out-of-state visitor, I wasn't sure what to expect, but this place blew me away! The shrimp and grits were pure comfort food--hearty, soulful, and out of this world. Gina, our warm and friendly server, recommended it, and she nailed it. David brought out hush puppies that were hands-down the best I've ever had (and I've tried them everywhere!). You can tell this small gem is all about down-home cooking done with love. Unlike big, cookie-cutter chain restaurants that churn out soulless meals, this place pours heart into every dish. It's clear they care about feeding people, not just making a buck. Can't wait to come back!

    Entrance

    Monique, the owner, is so friendly, and her food is amazing. The service was great, and both the fried and seared fish were delicious. Everything we tried was fantastic. If you're in Santee or the surrounding area, this place is a must-try!

    Menu (1 of 2)

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    3 months ago

    Ate dinner here tonight - the food was wonderful and our server Greg was fantastic. He was very attentive.

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    7 months ago

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    1 year ago

    Great food and service. Definitely will return when back in the area. Our server was very friendly too

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    2 years ago

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    1 year ago

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    9 months ago

    Food was greasy and scallops were under cooked. The seafood platter was small for the price and undercooked. The hush puppies were awesome.

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    9 months ago

    The service was very efficient. The food exceptional. Little dive but really good.

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    3 years ago

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    2 years ago

    Food is decent. Nothing spectacular. The restaurant could use a good cleaning. Service is pleasant.

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    Page 1 of 4

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    Cracker Barrel Old Country Store - Cracker Barrel, Santee

    Cracker Barrel Old Country Store

    3.0(125 reviews)
    0.3 mi
    $

    As always plenty parking; friendly staff; ; for a chain restaurant the food is delicious served…read morequickly and so many options for breakfast lunch and dinner ; the place is kept clean fun great for families

    We arrived at our hotel late in the evening and there are not many places open past 9pm in the…read morearea. Cracker Barrel was open until 11pm so we walked over. Justin was our server and he actually greeted us outside. We did not wait more than 2 minutes before someone greeted us at the host stand and actually apologized for making us wait! As we were walking to our table, we noticed the fireplace going and it had real wood! It was so cozy! Justin approached us not long after and offered us to order drinks. We ordered waters, wine, and beer. So the last time we dined at Cracker Barrel was almost 11 years ago because we became deathly ill. The last time, I do not believe they served alcohol so we were surprised seeing it on the menu. Our drinks were delivered quickly and Justin offered us to order dinner. Hubs ordered the Country Fried Turkey with mac and cheese and hashbrown casserole. I ordered the Country Vegetable Plate with green beans, coleslaw, mashed potatoes, and hashbrown casserole. Justin came back later and informed us there was only enough hashbrown casserole for one of us so he said I could order a side salad for no extra charge-sweet! Our food arrived not too long after and the salad was massive! Very fresh too! The Hashbrown casserole was good, everything else was okay but not magnificent. When we went to checkout, there were people taking way too long while their f'in kids were causing havoc in the store so we paid by using the QR code on the receipt. Our check was $45, which was pretty decent for 2 meals, 2 beers, and 1 wine. Oh but there were charges for getting apple butter and having a mix of biscuits and cornbread- was not aware of that when ordering. The bathroom was as clean as it could be but definitely needs to be upgraded. Best part of all, we did not get sick! We will be back if we are in the area again.

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    Cracker Barrel Old Country Store
    Cracker Barrel Old Country Store
    Cracker Barrel Old Country Store

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    Santee Seafood Bistro - seafood - Updated July 2026

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