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    Santee Seafood Bistro

    4.1 (123 reviews)
    Open 11:30 am - 8:30 pm
    Updated 1 month ago

    Santee Seafood Bistro Photos

    Business Info

    SANTEE SEAFOOD BISTRO ATMOSPHERE

    What's the vibe?
    Moderate noise
    Casual
    Good for kids

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    Recommended Reviews - Santee Seafood Bistro

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    Reviews With Photos

    Bob B.

    Santee, SC is Our favorite stopover place as we travel Florida - North Carolina several times a year: Nice hotels and several good restaurants. If you're in the mood for Seafood, we really like Santee Seafood Bistro - it's a block off of the main thoroughfare on a quiet street. They also have chicken, ribs, pulled port, brisket. The place is cordial, comfortable and welcoming. Wait staff is knowledgeable and friendly. The same goes for the cook who brings out your meal (a nice touch). I'm a beer guy (nice selection), but I think they have wine and mixed drinks too.

    Savory rich catfish stew in tomato broth over rice. Yum!
    Rich S.

    The Santee Seafood Bistro is a real find, especially if you crave catfish! It's a bright little standalone building just a couple of turns off I-95 at exit 96 onto Old Number Six Highway (SC-6), on Bass Dr at the end of Britain St. There's enough parking to the side and around back. There's outdoor seating on the north side, but it was a little chilly for that in Dec (2024). With a counter up front and tables to the left, there's plenty of seating for the size of the place. The hostess was welcoming and attentive, and the other guests were also friendly to us travelers. We came here for the hot fresh crispy fried whole bone-in catfish, and it was perfectly cooked in a simple light cornmeal salt and pepper breading just like we always had growing up. They also make a savory catfish stew in a rich tomato broth over rice. We were so full, but we did save just enough room for their fresh hot cobbler to finish. Get off that wearisome highway and enjoy some good regular comfort food in a bright place with nice people.

    Fried Seafood Platter
    Joshua R.

    If you want good seafood and friendly service you need to come here! We came in from a long day on the road and felt like we arrived home. The staff were very nice and we were able to get seated right away. They have a wide variety of seafood and bbq options. We ordered the fried seafood platter with a side of okra and the shrimp & grits with a side of collard greens. The seafood was very fresh and tasted great! The amount of food you get for the price is just right! Everything was very good and I highly recommend the collard greens!

    Inside

    As an out-of-state visitor, I wasn't sure what to expect, but this place blew me away! The shrimp and grits were pure comfort food--hearty, soulful, and out of this world. Gina, our warm and friendly server, recommended it, and she nailed it. David brought out hush puppies that were hands-down the best I've ever had (and I've tried them everywhere!). You can tell this small gem is all about down-home cooking done with love. Unlike big, cookie-cutter chain restaurants that churn out soulless meals, this place pours heart into every dish. It's clear they care about feeding people, not just making a buck. Can't wait to come back!

    Entrance

    Monique, the owner, is so friendly, and her food is amazing. The service was great, and both the fried and seared fish were delicious. Everything we tried was fantastic. If you're in Santee or the surrounding area, this place is a must-try!

    Menu (1 of 2)
    Courtenay O.

    After reading reviews, we decided to eat dinner here before checking into our cabin. We are so glad we did! We were warmly greeted by a gentleman before entering the restaurant. Once inside, we were directed to a corner table. He brought us our drinks while we read over the menus he gave us. While we were deciding, someone brought us hot, fresh, delicious hush puppies (3 in a basket). We don't usually like hush puppies, but these were awesome! Another young woman took our orders: crab cakes (4 mini) and cheesy grits for me, and shrimp dinner with corn on the cob for Husband. The restaurant was clean, busy, and everyone was friendly. Masks were worn by the staff and customers. Gloves were worn by anyone handling food. Tables were far enough apart for social distancing. We liked the music playing - Motown! Our food came in a good amount of time - hot and tasty. It was served in to go containers so we could take home whatever we could not eat here. This was due to CoVid - cleaner and safer. Our food was so good! We slowly ate everything, savoring every bite. We are so glad we trusted the best reviews and came here!

    Seafood platter fish scallops shrimps tartar sauce and cocktail sauce seasoned well. Good food

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    1 month ago

    Ate dinner here tonight - the food was wonderful and our server Greg was fantastic. He was very attentive.

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    11 months ago

    Great food and service. Definitely will return when back in the area. Our server was very friendly too

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    7 months ago

    Food was greasy and scallops were under cooked. The seafood platter was small for the price and undercooked. The hush puppies were awesome.

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    7 months ago

    The service was very efficient. The food exceptional. Little dive but really good.

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    2 years ago

    Food is decent. Nothing spectacular. The restaurant could use a good cleaning. Service is pleasant.

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    Page 1 of 4

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    Main Street Tavern

    Main Street Tavern

    4.4(9 reviews)
    31.1 mi
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    Main Street Tavern is one of the best spots in Sumter! From the moment you walk in, you feel like a…read moreregular. The bartenders are incredibly friendly and possess the perfect blend of professionalism and personality that makes the whole experience memorable. The food here is fantastic! The wings are absolutely phenomenal. They're perfectly cooked with a great variety of flavors to choose from. The pizza is outstanding with that delicious thin crust that hits the spot every time. You really can't go wrong with anything on the menu, but those wings and pizzas are must-tries! The atmosphere is cozy and welcoming with a great local vibe. It's the perfect place to unwind after a long day, catch up with friends, or enjoy some quality bar food and cold craft beer. They offer an impressive beer selection, featuring over 75 different domestic and craft options. One of the things I really appreciate is that it's a smoke-free bar, which makes for a much more comfortable environment. The prices are very fair, and the service is always professional and attentive. Whether you're a local or just passing through Sumter, Main Street Tavern is definitely worth a visit. Great food, great drinks, great people. What more could you ask for?

    Tavern on Main is one of the few bars in Sumter that you do not need to be a "member" of. There is…read moreno smoking inside which is nice, and they have a good selection of beers. On the weekends it is moderately crowded with people playing pool and the games the have in bar. Truth or Dare Jenga is always fun. :) The only issue I have with the bar is the perceived cleanliness level. I am sure it is clean, but they have gross old couches in the front area and it always smells a little bit like a restroom. Good place to grab a drink or two after dinner.

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    Main Street Tavern
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    Santee Seafood Bistro - seafood - Updated May 2026

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