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    Grille 221

    4.7 (27 reviews)
    Closed Closed

    Grille 221 Photos

    Business Info

    GRILLE 221 ATMOSPHERE

    What's the vibe?
    Good for groups
    Good for kids

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    Recommended Reviews - Grille 221

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    Reviews With Photos

    Double Bacon Cheeseburger
    Eddie R.

    Stopped by Grille 221 while I was visiting South Carolina for work, my coworkers highly recommend this place and it did not disappoint!

    On the door.
    Janet G.

    We were traveling through the area and decided to give this place a try. The parking lot was full when we stopped at lunchtime but there are other businesses in the little strip mall it's located in. We walked in and there was no hostess or sign but a server told us to pick a table and she would clean the table if it was dirty. My husband and I found a table for 2 and it was also clean so we sat down. The first thing we noticed was that it was pretty packed and there was only one server. Her name was Rebecca and she did a fantastic job taking care of all the customer needs in the place. The drinks are served in styrofoam cups and the plates are either styrofoam or paper baskets. The tea was fresh brewed and very good. We decided to split a chicken wrap and we both ordered side salads. Considering how busy they were the food came quickly. Everything was delicious. We were both very impressed with Rebecca and gave her a good tip. We hope everyone else did too. All of the patrons seemed patient and pleasant. If we're ever in the area we'll definitely stop here again.

    Nicki P.

    We could literally eat here everyday. Delicious open face roast beef sandwich and delicious hamburger. Friendly staff. A cool place to meet locals and hear what's going on around town.

    Chili cheeseburger with the works YUM
    Candace T.

    For what it is it's GREAT. The service was prompt and informed the meat was much better than usual.

    Jakes Chicken Wrap
    Jessie J.

    The wait was long, but it was worth it! We seated ourselves & the server came over promptly. There is one cook so at Lunch time (when we were there) it took a while to get our food. (Two hamburgers, grilled cheese, and Jakes Chicken wrap). The chicken wrap was suggested by the server and it was amazing! Very hearty, greasy, and stuffed full of veggies & chicken! The locals even stopped at our table to wish us a happy road trip.

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    Photo of Nico L.
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    3 months ago

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    2 days ago

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    12 days ago

    I've been going to Grille 221 since it opened. It's awesome. Best grilled chicken salad,hands down. It's a Spartanburg treasure.

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    2 years ago

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    4 years ago

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    2 years ago

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    5 years ago

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    3 years ago

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    2 years ago

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    4 years ago

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    3 years ago

    A solid burger joint. Good food, good service, and cold beer. Reasonable prices. Lots of neighborhood regulars.

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    Photo of Freddy M.
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    4 years ago

    Fascinating restaurant and delicious meals, great services, great cookers. Join and grab meals to eat!

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    2 years ago

    Good food, good service, definitely recommend. Had a burger & fries, not frozen food like most!

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    5 years ago

    Great place to chill with a bite to eat and watch sports!! Good food and friendly ppl you gots to stop in and try for yourself.

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    3 years ago

    Fantastic food Reuben around. Just wish it was open on Saturdays if even just lunch hours

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    6 years ago

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    4 years ago

    Local hometown corner bar that has amazing big fat juicy burgers and killer hand cut fries. Always great food and great service.

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    3 years ago

    This place is really good. I recommend the fried bologna sandwich. Good food with good service, nice people and relaxed atmosphere.

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    Photo of Adam R.
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    5 years ago

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    7 years ago

    Very nice local establishment. Nothing fancy here; sort of a neighborhood restaurant. Easy parking, convenient location.

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    5 years ago

    Great local find while traveling. Fresh ground burgers and excellent service. I would recommend this place be on your list if in the area.

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    8 years ago

    Great Food and Great atmosphere.. the service is great and the food quality is top notch! FYI Try the Cheese Balls!

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    Photo of Paul C.
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    11 years ago

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    9 years ago

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    11 years ago

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    15 years ago

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    12 years ago

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    Ask the Community - Grille 221

    Review Highlights - Grille 221

    The food is great, you have to try the fresh cut french fries and the cheeseburger club!

    Mentioned in 3 reviews

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    Smalls Sliders - Slider   Ig @yumthatgreenville

    Smalls Sliders

    (18 reviews)

    Love these little burgers! They're my guilty pleasure and I find myself returning regularly! The…read moreplace is cool looking shipping container architecture. Been here a handful of times and it's consistently great! Service is standard drive through but they're quick and haven't messed up my order yet I'll be back for sure!

    I really wanted to like this place, however they have several complaints…read more The best thing about Small Sliders is their service. The lady at the counter provided great customer service and food came out in 3-4 minutes. Considering how busy it was then, I like how efficient they are like Chick-Fil-A. Unfortunately that's where the compliments end. Pricing for the combos are slightly above what you would pay for at a fast food burger spot. In addition, the menu when ordering will make you feel like you're being nickel and dimed. I didn't mind paying for the queso, but paying extra for each of their sauces felt extra. There's only so few fast food restaurants that charge for extra sauce. The food portions were surprisingly small. Yes sliders are small, but the fries portion felt very sparse. It might have been the smallest side portion I've received at a fast food restaurant. The food is good for what it is. I'd prefer this over your typical fast food burgers, but by only so much. All orders are packaged to go, regardless if you choose to dine in or not. There are outdoor tables that you can sit there and eat if you'd like to. If you're looking for something quick in the area, good service, and a small burger meal, this in my opinion would be a good place to go. Otherwise, I can't suggest going here unless you really want to try it. I'd like to be wrong and try it again with some sort of change.

    Main Street Pub & Eatery - Fresh pork rinds with Bloody Mary dry rub.

    Main Street Pub & Eatery

    (119 reviews)

    $

    Everyone's food was delicious. The breakfast burrito was filling. The Bloody Mary was very good -…read morejust the right amount of heat. Service was friendly and quick. Parked on the street in the back for free, but there is also a pay parking lot that is free with validation.

    Suitcase Social Club Dispatch No. 47: "Timmy vs. The Lumberjacks"…read more If you've ever wondered what happens when a grown man with sales quotas, a mild caffeine imbalance, and the attention span of a golden retriever discovers competitive lumberjack sports streaming on the bar TV... well, allow me to submit Exhibit A. I wandered into Main Street Bar & Eatery for what was supposed to be a "quick bite between quotes." Instead, I became spiritually welded to a barstool while the TV blasted a man in flannel yeeting a chainsaw like it owed him money. And the fried pickles. Good grief. Those things ambushed me. One minute I'm thinking "I'll just have a snack," and the next I'm waist-deep in a basket of fried circles of temptation, crunching my way into oblivion while pretending to "work." My laptop was open, sure, but let's not lie to ourselves -- I got absolutely nothing done. I was too busy yelling advice at professional lumberjacks like I'd trained for this moment my whole life. Tim the Suitcase Regular Rating Breakdown: * Atmosphere: Cozy but with the unpredictable energy of a log-rolling final * Food: Fried pickles that could ruin a man's productivity in the best possible way * Service: Friendly, fast, and kindly nonjudgmental of whatever fever dream I was living in * Entertainment: 10/10 involuntary lumberjack immersion If you're looking for a place where you can lose an entire afternoon under the noble banner of "I swear I'm still working", Main Street Bar & Eatery is the arena. Suitcase Social Club™ stamp of approval: Earned.

    Grille 221 - steak - Updated May 2026

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