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Highway 21 Seafood

4.9 (24 reviews)
InexpensiveSeafood Markets
Closed 10:00 am - 5:00 pm

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Recommended Reviews - Highway 21 Seafood

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We stopped by Highway 21 in Beaufort SC on our way to Key West. The seafood was exceptional and at a super affordable price! We picked up fresh shrimp, oysters and crab cakes! When we got to our campsite in Savannah GA we cooked all of the seafood and had superb dinner! Highly recommend you stop by and get the best seafood from Highway 21!

The low country boil I made with 4 lbs of fresh large shrimp from Hwy 21 Seafood
Chris W.

Great selection of fresh shrimp in all sizes with heads on and off. They also have a fine collection of oysters, crabs and fish. Great prices, too. They probably had more but I had sensory overload!! This will be my seafood market from now on

The small but mighty Hwy 21 Market
Regina M.

Top notch and recommend for fresh seafood on the GO! We were on our way out of town and wanted one last hurrah and three residents and two visitors recommended we stop at HWY 21 Market. Great prices and outstanding service. We had choices galore and settled on a single bushel of oysters - the cluster bag was too big for our cooler ;-) upgrading to a bigger cooler next time. We also secured a sheepshead and a bundle or scallops. You cannot beat the freshness and prices in my opinion were very reasonable for what we received. We will be making Hwy 21 and its awesome staff a permanent stop on our way in and out of town in low country. Among selection: whiting, tilapia, sheepshead, clams, crabs, shrimp, oysters, conch and many many more. Don't even try to drive by and miss this spot - although you might pass if going by too fast. You won't regret it and consider this a TOP bonus of visiting the area. Glad we took the advice.

Pete S.

What a great little find. Small, medium and large shrimp. Head on shrimp. Mussels, scallops, crab legs. Several different types of fish fillets as well as whole fish. Nothing fancy just allot of seafood. Looks like allot of locals buying from there also.

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1 month ago

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2 months ago

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3 years ago

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1 year ago

Fresh and friendly staff.will return when in the area. Don't underestimate because of the location.

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11 months ago

They had everything I needed plus a whole lot more!! Great staff Highly recommend Will definitely be back for more

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1 year ago

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2 years ago

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1 year ago

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1 year ago

Great fresh seafood.The x large shrimp were very good and the salmon was probably the best we' ve ever had A sold 5 out of 5.

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1 year ago

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4 years ago

These guys are the best. They have the best seafood around. They are extremely helpful. Do yourself a favor and stop by, take your cooler.

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4 years ago

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9 years ago

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3 years ago

Freshest seafood! The staff is always helpful and kind. We always plan a visit when we are in Beaufort.

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6 years ago

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10 years ago

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12 years ago

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7 years ago

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8 years ago

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10 years ago

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7 years ago

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11 years ago

Great local secret!! Good fresh seafood and great prices!! They also can steam your shrimp and crabs also.. Great staff.

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10 years ago

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11 years ago

Worth the trip! Beautiful, fresh shrimp and clams, fair prices, service with a smile, packed on ice. We will be back.

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Ask the Community - Highway 21 Seafood

Do they sell other seafood or just shrimp?

All kinds of seafood.

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Review Highlights - Highway 21 Seafood

Beautiful, fresh shrimp and clams, fair prices, service with a smile, packed on ice.

Mentioned in 4 reviews

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Highway 21 Seafood - seafoodmarkets - Updated May 2026

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