La Cà Granda ("the big house") was once used by the Milanese people to describe the original Ospedale Maggiore complex. That was founded in 1456 by the Duke of Milan, Francesco Sforza (you might recognize that name from the Sforza castle). Originally to provide medical care for the city's poorest people and reorganizing medical care from multiple institutions into a single building.
Today, Cà Granda covers an area of 43,000 square meters (10.6 acres). Shaped like a huge rectangle, a look at a Milan satellite image makes it instantly recognizable (straight line southeast from the castle across the Duomo).
Renaissance-style round arches along the massive front of the building which was extensively damaged by Allied air raids during WW2. After those repairs, the University of Milan moved in and today it is the home of the art institute.
Much of the structure is open for tours. If you appreciate classic architecture, it's worth a look.
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