If you go to Rothenburg ob der Tauber, very famous tourist site by train, this station is main…read moregate. From here to the old historic city center, Marktplatz square, it take a maximum of 10 minutes for you to reach at the old historic city in Rothenburg on your foot.
There are several coin-operated lockers in this station. So, if you feel so heavy of your bag, you had better leave your bag in the lockers, and can easily get on sightseeing on the rural and peace old city of Rothenburg. I forgot the price of the lockers. In my case, I didn't use it because I left my suitcases in the hotel where I stayed.
If you're coming from a larger city like Frankfurt or Munich, you'll likely have to make several train changes. Alternatively, you can buy your train ticket to the Ansbach station and take a bus 16 kilometers to Rothenburg.