If you live in the Southern part of Berlin, you will probably go through here…read more
There is a Deutsche Bahn ticket/travel office there with a staff that can (mostly) help you in English if you cannot navigate the bahn.de website, or need tickets to places like Poland. This is a major debarkation point to points South in the intercity / international rail. Prague, Dresden, Leipzig amongst them.
The station itself offers shopping and noshing aplenty. Open in 2006, its shiny, new and well designed. Nice station - your pedestrian Sbahn connection to the IKEA and Bauhaus stores to the South, and a critical node in the Berlin light rail.