As difficult as it can be to do laundry in Prague, noted elsewhere, this place is good and…read moreconvenient if you're staying near Vaclavské Náměstí. Or, about a 2-5 minute walk from the metro.
The woman working the counter spoke a little English, and was very nice. No problems understanding what I wanted or when it would be done.
A little pricey: 550 kč for a load including two shorts and pants being pressed. I think the laundry alone would have been 180 kč, so more reasonable. 3 hours for everything. Done well and on time.
If you're staying near Vaclavské Náměstí and need some laundry done, it's worth checking out.